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In the new review, we noted the identification as well as the characterization of a brand new atypical opioid receptor with one of a kind adverse regulatory Houses in direction of opioid peptides.1 Our success showed that ACKR3/CXCR7, hitherto generally known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is additionally a wide